To guard your heart, and to avoid being anybody's fool, it is actually quite important to accept in your mind that some people are write-offs.Transsexuals can be put into positions of extreme anxiety when faced with the prospect of what some people will think or say. Much of this anxiety can be alleviated by simply telling yourself the worst is going to happen, and you don't care. While they may never accept you, and they may never be okay, you will.
I have a great deal of experience with this. One example would be that all of my female friends at school know about me, but I haven't told a single straight male. I have two male best friends, Jamie and Cory, and I've already cut myself off from them emotionally and am in the process of coming up with a decent cover story to ensure that I never see them again. Will I miss them? Yes. Do I think I could keep them around if I tried? No. Although I do believe in most cases it is better to actually give people a chance, I also feel that sometimes, it just isn't worth it. A few unexpected allies can crop up, but if the warning signs and ominous clouds are looming over a relationship, it may be best to cut and run.